#2123
Distances are standardized. First slot is always awfully tight. If the GPU got a backplate it's not happening.
So if the first slot is a x1 slot no problem, since the GPU will go in the second slot. Otherwise it's not happening.
D15S is very close with both fans. Either is probably overkill though.
#2124
Yes.
Yes there are. http://pcpartpicker.com/products/motherboard/#f=8&E=1,3&sort=a8&e=31,15,30,14,6,8