iridescentFUZZElepimpTLR and Harb anyone?
I think Zebbo+Mirelin, yuki+bonobo and B4nny+Shade/lanksy+Shade are the only combos in recent TF2 history I'd rate as consistently being close to, or on the same level as Mike and Knoxxx.
TLR and harb s8 was unarguably the best combo since reptile + 1 until Mike / Knoxxx and even then it would be a difficult tossup for me although Mike is a fucking beast
on mix^ TLR wass not as much of a high impact player as Mike but he had his role and he filled it really well
Zebbo Mirelin i49 was an insane combo but @ i52 they were really predictable and really easy to force into bad spots
yuki was probably the best pocket soldier @ i49 and i52 but that's really debatable, however I would not rate bonobo as high I as would for some of these other medics
B4nny takes a large focus of the team when he is on pocket and lansky often did just as much with a lot less although both are/were formidable combos when paired with shade
rando and cozen was also an incredible combo, arguably better than lansky / shade when they played, rando and cozen definitely played a larger role in their team
also
SAINTS
https://www.youtube.com/watch?v=-kQTsGG3TQE