The museum that I work at's building was constructed in 1890, as a sort of department store for railroad shops (basically whatever goods came in by rail) but by 1917, those goods had become so ubiquitous that they no longer needed their own special store and were instead spread throughout all the shops in town. Then, in the 1920s, it became a car dealership (cars were tiny and dealerships were often strictly indoor affairs), but the crash in 29' took them out, and a local family that specialized in furniture making, and undertaking, moved in. This wasn't all that uncommon, as whoever made a chair or table could also make a coffin, and coffins tended to be a fairly reliable business so if your fancy chair didn't sell, you could still stuff somebody in a pine box.
The entire basement was also remodeled to accommodate embalming services, which had become extremely common after 1907 (various laws about just burying grandma in the backyard and its illegality were enacted at the state level here in Indiana). They lasted in that location until 1954 when Sears took over the building and did Sears stuff there until 1983 - whereupon the Museum eventually moved in.
When they were remodeling to facilitate the museum, the contractors had to take pictures of the entire process, being as the building was flagged as an historic landmark. "Orbs" as spooky-ghosty enthusiasts call them are legion in every photograph - I like to think they're just dust particles getting caught by the flash, but there's just no convincing some people.
Furthermore, the entire basement is still set up to embalm corpses. The first thing they did was fill in, with concrete, the pit wherein bodies were drained. In the 1930s the way you prepared a corpse was to essentially lower it down on a gurney and puncture some important arteries, and then let the blood and other fluids naturally drain out by manipulating the gurney.
On top of that, there is the full skeleton of a serial killer in boxes - I've labeled them "Hubbard Bones" on one side, and leave the unlabeled side exposed so I can scare interns with them. Basically, I'll ask them to see what is in those boxes and they'll go open them. I've positioned his skull in such a way that he is cheerily saying "Hi!" to them - or at least what I would imagine would be his cheerily saying "Hi!" with no skin n' such. He killed 7 people in 1854, was publicly executed on the courthouse lawn, and then his body was parted out for illegal dissection, and then used in the old high school's science lab as an anatomy piece until 1924 when his bones were turned over to the museum. We also have his death mask, made by a local doctor, which includes sick sideburns.
A ghost hunter from Indianapolis who has a podcast or internet show of some sort (I didn't look at it) asked to come do a show. The only spooky thing he found was a "cold spot" just before entering the embalming room, at which point I had to ruin his fun and point out that there is a cold air output vent just above where he was standing that runs 24/7 as a means of climate controlling the basement which we use for artifact storage.
So in short, no ghosties, but if there were such a thing, I probably should have encountered one by now.